High-affinity choline uptake protein bett

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August undefined, 2024

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … WebHigh affinity choline uptake is generally believed to be the rate-limiting step in acetylcholine synthesis in cholinergic neurons and is essential for cholinergic ... hCHT1 protein is composed of 580 amino acids with a predicted molecular mass of 63 kDa. Sequence analysis of the hCHT1 protein predicts 13 transmembrane domains (13, 20, 21).

CHT1 (High-affinity Choline Transporter) SpringerLink

Web25 de mar. de 2024 · Choline uptake and LPS decoration protects bacteria from osmotic pressure, and enables avoiding the immune system recognition. Choline uptake is provided in P. mirabilis O18 by a high-affinity choline transport protein BetT. Choline gained in this way is involved in the glycine betaine biosynthesis pathway, ... Web5 de mai. de 2024 · The high-affinity choline transporter CHT1 mediates choline uptake, the rate-limiting and regulatory step in acetylcholine synthesis at cholinergic presynaptic … phone shop thomas street

Choline Uptake - an overview ScienceDirect Topics

WebIn addition to the industrial and biomedical applications of lithium, information on the tolerance of microorganisms to high Li concentrations in natural biological systems is limited. Strain LCHXa is a novel free-living Gram-positive, non-motile WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) Web8 de mar. de 2006 · The high-affinity choline transporter at the molecular level. Despite the fact that the high-affinity choline uptake system was described in the 1960s, the genes for the high-affinity choline transporter proteins (CHT1) of Caenorhabditis elegans and rat have only recently been cloned (Okuda et al. 2000). phone shop thanet

Pseudomonas syringae BetT Is a Low-Afﬁnity Choline

D616_p92038 High-affinity choline uptake protein BetT []

Web5 de mai. de 2024 · The high-affinity choline transporter CHT1 mediates choline uptake, the rate-limiting and regulatory step in acetylcholine synthesis at cholinergic presynaptic … WebHigh-affinity transport of choline-O-sulfate and its use as a compatible solute in Bacillus subtilis High-affinity transport of choline-O-sulfate and its use as a compatible solute in … phone shop thurlesWebA choline uptake system with a high affinity for choline has long been assumed to be present in cholinergic neurons. Very recently, the molecular entity for the high-affinity … how do you spell blah

"WebA molecular phylogenetic analysis of salt-tolerance-related genes was carried out using complete genome sequencing data available for 26 Sinorhizobium meliloti strains and for 25 bacterial strains belonging to 17 genera. It was revealed that the genes of the first and the second stages of the response to salt stress (aqpZ, trkH, and trkA, and betICBA) have … " - High-affinity choline uptake protein bett

High-affinity choline uptake protein bett

WebIn cholinergic neurons, high-affinity choline uptake in presynaptic terminals is the rate-limiting step in acetylcholine synthesis. Using information provided by the Caenorhabditis elegans Genome ... Web27 de fev. de 2015 · Only strains FB24 and A6 contained both the choline binding protein A gene and high-affinity choline uptake protein (BetT) gene; only strains M2012083, TC1, Sphe3 and Rue61a contained the choline ...

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WebThis transporter has a particularly low affinity (K(m) of 876 microM) and high capacity (V(max) of 80 nmol/min/mg of protein) for choline transport relative to other known … Webmax of 80 nmol/min/mg of protein) for choline transport relative to other known BCCTs. Although BetT activity increased in response to hyperosmolarity, BetT mediated signiﬁcant uptake under low ...

Web29 de mar. de 2024 · This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from … Web31 de out. de 2000 · Na +-dependent, high-affinity choline uptake in cholinergic neurons is the rate-limiting step in acetylcholine synthesis.Here we report the molecular cloning and functional characterization of the human high-affinity choline transporter (hCHT1). The hCHT1 exhibits significant homology with known members of the Na +-dependent …

WebThe nature of the high affinity uptake system guarantees that cholinergic cells will always receive priority access to all available choline. Because of this, choline will be … Web28 de mar. de 2003 · Uptake of choline by the high-affinity choline transporter CHT1 is the rate-limiting step in neuronal acetylcholine (ACh) synthesis. Here, we investigated by RT …

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. …

WebCholine uptake (Vmax) increases up to 3 months of age and decreases significantly from 1 to 7 years of age ( Fig. 6A; Table III ). A further indication of a reduced synthesis with … how do you spell blastoiseWeb3 de mar. de 2024 · The betT gene encodes the high-affinity choline uptake protein BetT, betI encodes the choline-responsive BetI repressor for both choline uptake and betaine synthesis (Scholz et al. 2016), and opuA is … phone shop thurmastonWeb1 de jan. de 2024 · The high-affinity choline uptake activity in patients with these diseases was predicted to be diminished by mutations that impaired CHT1 function and/or trafficking. There is a functionally relevant, nonsynonymous single nucleotide polymorphism in the coding region of the human CHT1 gene (c.265A>G, rs1013940) (Okuda et al. 2002 ). how do you spell blankWeb8 de mar. de 2006 · The high-affinity choline transporter at the molecular level. Despite the fact that the high-affinity choline uptake system was described in the 1960s, the genes … how do you spell blancmangeWeb1 de mar. de 2007 · For osmoprotection, Escherichia coli can synthesize glycine betaine from externally supplied choline by the Bet system (betTIBA products). The major carrier of choline is the high-affinity, proton-driven, secondary transporter BetT, which belongs to the BCCT family of transporters. Fusion proteins consisting of N-terminal fragments of … how do you spell bleachersWebThe presumed binding proteins of both ABC transporters were shown to be lipoproteins. ... -choline uptake via OpuB (K(m) = 1 microM; Vmax = 21 nmol min-1 mg-1 protein) and OpuC (K(m) = 38 microM; Vmax = 75 nmol min-1 mg-1 protein) revealed that each of these ABC transporters exhibits high affinity and substantial transport capacity. phone shop thornburyWebIn cholinergic neurons, high-affinity choline uptake in presynaptic terminals is the rate-limiting step in acetylcholine synthesis. Using information provided by the … how do you spell bleach