Chip28 protein
WebCHIP28 is an abundant integral membrane protein in RBCs and renal tubules, and Xenopus laevis oocytes injected with CHIP28 RNA exhibit high osmotic water permeability, P f [Preston et al. (1992) Science 256, 385-387]. Purified CHIP28 from human RBCs was reconstituted into proteoliposomes in order to establish if CHIP28 is itself the functional ... WebThe sites of water transport along the nephron are well characterized, but the molecular basis of renal water transport remains poorly understood. CHIP28 is a 28-kD integral …
Chip28 protein
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WebThe native CHIP28 protein is a noncovalent assembly of four subunits (12) and is physically similar to certain membrane channels (hence, CHIP28 = channel-forming integral protein of 28 kD). The cDNA encoding CHIP28 has been isolated (13), and the deduced amino acid sequence predicts an integral membrane protein with six bilayerspanning domains ... WebApr 1, 1992 · The CHIP28 protein is an abundant integral membrane protein in mammalian RBCs and renal proximal tubules and belongs to a family of membrane proteins with unknown functions. Oocytes from Xenopus laevis microinjected with in vitro-transcribed CHIP28 RNA exhibited increased osmotic water permeability; this was reversibly …
WebPreston GM, Carroll TP, Guggino WB, Agre P. “Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.” Science. 1992 Apr 17;256(5055):385-7. Agre P, Casella JF, Zinkham WH, McMillan C, Bennett V. “Partial deficiency of erythrocyte spectrin in hereditary spherocytosis.” Nature. 1985 Mar 28-Apr 3;314(6009):380-3. WebG M Preston; T P Carroll; W B Guggino; P Agre; Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.. Science 1992, 256, 385–387, . G M Preston; J S Jung; W B Guggino; P Agre; The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel.. Journal of Biological Chemistry 1993, 268, 17–20, .
WebThe same protein was purified by chance by Agre group in Baltimore, USA, in 1988, who called in 1991 the protein CHIP28 (CHannel forming Integral membrane Protein of 28 kDa), suggesting that it may play a role in linkage of the membrane skeleton to the lipid bilayer. In 1992 the Agre group identified CHIP28's water transport property. WebCHIP28 is an integral protein of apparent molecular mass 28 kDa, which is abundant in membranes of red cells and renal proximal tubules (Denker et al., 1988). The cDNA encoding CHIP28 revealed homologies with a family of mem- brane proteins expressed in diverse species and tissues, in- ...
Web(Figure omitted) The CHIP28 protein is related to the major intrinsic protein from bovine lens, MIP26, a channel through which lens fiber cells may absorb interstitial fluid (14). …
WebOct 30, 2006 · We have thus a world priority in the discovery of the first water channel in the RBC membrane, that was re-discovered by chance by the group of Agre (Baltimore, … sample of airway billWebMedChemExpress(MCE) 试剂. 已认证. 品牌介绍 sample of amending barangay tax ordinancehttp://www.vivo.colostate.edu/hbooks/pathphys/topics/aquaporins.html sample of an analysis paperWebThe magnitude of CHIP28-mediated water flux (11.7 X 10-14 cm3/s per CHIP28) corresponds to the known Pf of intact RBCs. These results demonstrate that CHIP28 … sample of altar designWebJun 1, 1993 · The coinjection of an antisense oligonucleotide for CHIP28 protein, at an assumed > 100-fold molar excess, with either cortex, medulla, or papilla mRNA reduced the expression of the water permeability by approximately 70, 100, and 30%, respectively. Exposure of the oocyte to cAMP for 1 h resulted in a further increase in Pf only in oocytes ... sample of alternative hypothesisWebAquaporins (AQPs) play a pivotal role in the cellular transport of water and many other small solutes, influencing many physiological and developmental processes in plants. In the present study, extensive bioinformatics analysis of AQPs was performed in Aquilegia coerulea L., a model species belonging to basal eudicots, with a particular focus on … sample of an action plan templateWebOct 30, 2006 · However, in addition to the 28 kDa component, this protein had a 35-60 kDa glycosylated component, the one detected by Benga's group. Only in 1992 the Agre's group suggested that "it is likely that CHIP28 is a functional unit of membrane water channels". In 1993 CHIP28 was renamed aquaporin 1. sample of an audit plan